ISAAC N. DUKE was born January 28, 1828. His father, Washington Duke, was a native of Virginia, where he was reared and married; then moved to Tennessee, and later came to Kentucky, locating in Ohio County, where he died. His wife, Elizabeth Vaught, of Virginia, is also deceased. They have twelve children — four living in Kentucky. Isaac N. is the seventh child, was reared on a farm, and at twenty-one began for himself, working by the month, and later bought a farm, where he now lives. He owns 150 acres, 100 under cultivation. He set out an orchard, built a residence, fenced and cleared the ground on which his residence now stands. He raises tobacco, wheat, corn and oats, etc., for which he finds a ready sale. He also raises stock. November 23, 1851, Mr. Duke married Martha J. Tinsley, of this county, daughter of Absalom and Mary (Kerns) Tinsley. She died December 4, 1881, a member of the Methodist Church. They were the parents of nine children, five living: John A., farming; Lucy, wife of Charles Wimpsatt; Stephen E.; Prudie M.; and Ada E., the last two at home keeping house. Mr. Duke, with his children, except Ada E., are Methodists. Politically Mr. Duke is a Democrat; prior to the war he was a Whig. He is a school trustee. He has taken all the degrees to Master Mason in the Masonic order. His personal standing is the result of his own industry.
Source: J. H. BATTLE, W H. PERRIN, & G. C. KNIFFIN 1895
Mr. Duke died 14 March 1905 in Ohio County and is buried in the Duke Cemetery, Dukehurst, Ohio County, KY.